Recent work by Eric Klopack, a recipient of the EdDem Network’s Pilot Award Program, and colleagues examines whether blood-based biomarkers can help explain sociodemographic differences in cognitive aging. Using data from the Health and Retirement Study, the authors test which biomarkers best predict cognitive dysfunction and cognitive impairment onset, and how much these markers account for disparities by age, race and ethnicity, and education. The infographic below summarizes key findings from the study. A full citation and link to the published paper are provided below.
Klopack, E. T., Farina, M. P., Thyagarajan, B., Faul, J. D., & Crimmins, E. M. (2025). How much can biomarkers explain sociodemographic inequalities in cognitive dysfunction and cognitive impairment? Results from a machine learning model in the Health and Retirement Study. Journal of Alzheimer’s disease: JAD, 106(1), 54–68. PMC12385895. https://doi.org/10.1177/13872877251338063
Infographic designed by Deena Shariq